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本文总结了１８例经临床和病理确诊的结节性多动脉炎（ＰＡＮ），分析其临床及清理特征，发现：①微型ＰＡＮ占绝大多数，肾小球和肾小管－间质损害严重，②肾外以贫血、心脏、消化道、盯脏、神经系统损害多见，高血压发生率较高；③绝大部分的肾脏有免疫复合物沉积，抗中性粒细胞胞浆抗体（ＡＮＣＡ）阳性率低（２３％）。对ＰＡＮ的早期诊断及治疗选择有赖于早期肾活检，ＡＮＣＡ只能作为辅助诊断工具，阴性并不能否定ＰＡＮ诊断。同时本文资料亦表明，ＰＡＮ的肾脏损害以免疫复合物介导为主，部分与ＡＮＣＡ相关。
This article summarizes 18 cases of clinical and pathological diagnosis of nodular polyarteritis (PAN), analysis of its clinical features and clean-up, found that: ① mini-PAN accounted for the vast majority of glomerular and tubular-interstitial damage, ② renal anemia, heart, digestive tract, stare, nervous system damage more common, high incidence of hypertension; ③ most of the kidneys have immune complex deposition, anti-neutrophil cytoplasmic antibody (ANCA) Positive rate is low (23%). The early diagnosis and treatment of PAN depends on the choice of early renal biopsy, ANCA only as a diagnostic tool, negative and can not deny the diagnosis of PAN. At the same time, the data in this paper also show that the renal damage of PAN is mainly mediated by immune complex, and partly related to ANCA.