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目的观察2型糖尿病患者与非糖尿病患者散瞳后瞳孔直径的大小(以下糖尿病均指2型糖尿病)。方法将2009年10月-2011年12月在眼科门诊就诊及因糖尿病性视网膜病变行激光治疗的住院患者30例(60只眼)纳入糖尿病组,另将因视网膜静脉阻塞、视网膜坏死综合征、视网膜裂孔等需要行视网膜激光光凝治疗的50例(61只眼)患者纳入对照组,两组均用复方托吡卡胺滴眼液散瞳,每5分钟1次,共4次,30 min后用瞳孔尺测量自然光线下瞳孔直径的大小并进行比较。结果在相同药物、相同时间、相同剂量的作用下,糖尿病组患者瞳孔直径变化差值较对照组小,两组比较差异有统计学意义(P<0.01)。结论糖尿病患者散瞳后瞳孔直径明显小于非糖尿病患者,在临床工作中应考虑瞳孔不易散大带来的不利因素。
Objective To observe the size of pupil diameter after dilation in patients with type 2 diabetes mellitus and those without diabetes mellitus (the following types of diabetes refer to type 2 diabetes mellitus). Methods 30 cases (60 eyes) of hospitalized patients who were treated in ophthalmology clinic and laser treatment of diabetic retinopathy from October 2009 to December 2011 were included in the diabetic group. The other patients were diagnosed as retinal vein occlusion, retinal necrosis syndrome, Retinal tears and other retinal laser photocoagulation treatment required 50 cases (61 eyes) patients were included in the control group, both groups were treated with compound tropicamide eye drops mydriasis, once every 5 minutes, 4 times, 30 min Pupil ruler after measuring the size of the pupil diameter under natural light and compared. Results The difference of pupil diameter in patients with diabetes mellitus was smaller than that in control group under the same drug, same time and same dose. There was significant difference between the two groups (P <0.01). Conclusion Diabetic patients with mydriatic pupil diameter was significantly smaller than non-diabetic patients in the clinical work should consider the pupil is not easy to disperse the unfavorable factors.