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目的:研究并观察利福喷汀治疗耐利福平肺结核的临床治疗效果。方法:选取我院2012年7月-2014年7月收治的80例肺结核患者为研究对象,依据不同的治疗方案将患者分为两组,对照组和观察组,每组40例。治疗疗程为1年,观察痰菌阴转、肺部病灶吸收及不良反应情况。结果:治疗1年后对照组和观察组的痰菌阴转率分别为62.5%和30.0%,胸部X线改善有效率分别为45.0%和15.0%,组间比较,差异具有统计学意义(P<0.05)。结论:利福喷汀治疗耐利福平肺结核具有很好的临床治疗效果。
Objective: To study and observe the clinical efficacy of rifapentine in the treatment of rifampin-resistant pulmonary tuberculosis. Methods: Eighty patients with tuberculosis who were treated in our hospital from July 2012 to July 2014 were selected as study subjects. Patients were divided into two groups according to different treatment plans: control group and observation group, 40 cases in each group. Treatment for 1 year, observed sputum negative conversion, absorption of lung lesions and adverse reactions. Results: After 1 year of treatment, the sputum negative conversion rates in the control group and the observation group were 62.5% and 30.0%, respectively, and the improvement rates of chest X-ray were 45.0% and 15.0% respectively. There was significant difference between the two groups (P <0.05). Conclusion: Rifapentin has good clinical efficacy in the treatment of rifampin-resistant pulmonary tuberculosis.