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目的:验证乳腺癌前哨淋巴结定位与活检技术的可行性和前哨淋巴结能否准确预告腋淋巴结状况。方法:用美蓝(亚甲蓝)对32例乳腺癌患者进行术中及术后前哨淋巴结定位与活检。结果:26例(81.25%)检出前哨淋巴结,且均集中在 level Ⅰ区域。用美蓝定位前哨淋巴结预告腋淋巴结转移的敏感性为77%(7/9),准确性为80.76%(21/26),特异性为82.3%(14/17),假阴性率为22%(2/9)。结论:前哨淋巴结虽能预测腋淋巴结状态,但要取代腋淋巴结清扫还需进一步研究。
Objective: To verify the feasibility of sentinel lymph node localization and biopsy in breast cancer and whether sentinel lymph node can accurately predict axillary lymph node status. Methods: Intraoperative and postoperative sentinel lymph node mapping and biopsy were performed on 32 patients with breast cancer using methylene blue (methylene blue). Results: Sentinel lymph nodes were detected in 26 cases (81.25%), all of which concentrated in the level Ⅰ area. The sensitivity of sentinel lymph node mapping with methylene blue to the axillary lymph node metastasis was 77% (7/9), the accuracy was 80.76% (21/26), the specificity was 82.3% (14/17), the false negative rate was 22% (2/9). Conclusion: Although the sentinel lymph node can predict the status of axillary lymph node, it is necessary to further study to replace axillary lymph node dissection.