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本文报告一例肺性肥大性骨关节病,应用硫酸阿托品治疗后,握力、活动范围等项检查显示反应良好。作者认为此种化学方法阻断迷走神经取得的疗效,支持肺性肥大性骨关节病的迷走神经反射的发病学说。病例报告:49岁,男性,既往健康,于1976年发现右大腿患纤维组织细胞肉瘤,伴有骨和肺的转移。经18个月的化疗,局部和转移的病灶消失。1978年6月出现干咳,活动时呼吸困难,胸片示肺部病变复发。1978年9月再次因严重的关节痛,指(趾)、腕和膝关节严重肿胀,胸片肺部周围有巨大团块影,手、胫腓骨下1/3骨片示骨膜炎,两下肢非指凹性浮肿和触痛性男性乳房发育,左右手握力分别为5 10mmHg,平均皮肤温度左右手分别为
This article reports a case of pulmonary hypertrophic osteoarthropathy, application of atropine sulfate treatment, grip strength, range of activities and other items showed good response. The authors believe that this chemical method to block the efficacy of the vagus nerve to support the pathogenesis of vagal reflex of pulmonary hypertrophic osteoarthritis. Case Report: A 49-year-old, male, formerly healthy, had a fibrohistiocytosarcoma in the right thigh found in 1976 with bone and lung metastases. After 18 months of chemotherapy, local and metastatic lesions disappear. June 1978 dry cough, breathing difficulties during activity, chest X-ray showed lung disease recurrence. In September 1978 again due to severe joint pain, finger (toe), severe swelling of the wrist and knee, chest X-ray film around the lungs, hands, tibia and fibula lower thirds showed periostitis, both lower extremities Non-dimpled edema and tenderness of male breast development, left and right hand grip were 5 10mmHg, the average skin temperature left and right hands were