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化学感受器瘤(Chemodectoma)为一种少见的肿瘤,虽可发生于有化学感受器的任何部位,但在颅内或椎管内者仅个别,现将我们经手术证实的两例报告于下。例1薛×,女,17岁。因逐渐加重的右侧面瘫、面部麻木、听力减退及上肢共济失调3年于1975年11月13日入院。查体发现:两眼球呈水平性震颤,右面部痛触觉减退,右眼球外展受限,右侧周围性面瘫和神经性耳聋,左足划跖反射伸性。外耳道正常,无脓血或肿物外隆,鼓膜完好无外突现象。X 线颅片正常。气脑造影示中脑导水管和第四脑室向左后移位。拟诊为右侧桥脑小脑角占位性病变。开颅发现瘤体呈地毡样生长,自小脑右半球前部向桥脑侧面脑底伸延,无明确的包膜。因止血困难、瘤体面积过大,只作活检和减压术。病理检查:瘤组织由上皮样细胞组成,排列成巢状;胞体较大,原浆布满嗜伊红颗粒,核清晰均染,卵圆形,未见核仁。瘤细胞巢间有丰富的血窦,夹杂少许纤维组织(附图)。病理诊断:化学感受器瘤。
Chemodectoma is a rare tumor that can occur anywhere with chemoreceptors but only in the intracranial or intraspinal area. We report two surgically confirmed cases. Example 1 Xue ×, female, 17 years old. Due to the gradual aggravation of the right facial paralysis, facial numbness, hearing loss and upper extremity ataxia hospitalized on November 13, 1975. Physical examination found: the two eyes were horizontal tremor, right facial pain sense of touch diminished right eyeball outreach limited, right facial paralysis and neurological deafness, left foot plantar reflex extensor. External auditory canal normal, no abscess or blood tumor bulging, tympanic membrane intact no sudden phenomenon. X ray cranial normal. Cerebral angiography showed the middle cerebral aqueduct and the fourth ventricle displaced to the left. To be diagnosed as right cerebellopontine angle occupying lesions. The craniotomy showed a felt-like growth of the tumor, extending from the anterior part of the right hemisphere of the cerebellum to the lateral base of the pons in the cerebellum without a definite envelope. Difficult to stop bleeding, tumor area is too large, only for biopsy and decompression. Pathological examination: tumor tissue consists of epithelial-like cells, arranged in nests; large body cell, puree covered with eosinophilic particles, clear nuclear staining, oval, no nucleolus. The nests of tumor cells are rich in sinusoids, mixed with a little fibrous tissue (with photos). Pathological diagnosis: chemoreceptors.