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有关乙型肝炎病毒(HBV)表面(s)、核心(c)和e系统免疫学标志的最新研究进展改进了检测技术,从而提高了检测的灵敏度和特异性,同时也加深了其间的联系性。本文着重从HBV三大免疫系统间的横向联系角度,解释其动态的临床与流行病学意义。一、急性乙型肝炎由临床发病2～4周之前即可出现乙肝病毒表面抗原(HBsAg)阳性。出现早晚与感染量有关,如为创伤感染或输血后肝炎,发病最快者可仅隔1周的潜伏期。
Recent advances in immunological labeling of Hepatitis B virus (HBV) surface (s), core (c), and e systems have improved detection techniques to increase the sensitivity and specificity of assays while also deepening their association . This article focuses on the clinical and epidemiological implications of its dynamics from the perspective of the horizontal relationship between the three major immune systems of HBV. First, acute hepatitis B clinical onset of 2 to 4 weeks before the emergence of hepatitis B virus surface antigen (HBsAg) positive. Appear sooner or later with the amount of infection, such as traumatic infection or post-transfusion hepatitis, the fastest onset may only 1 week incubation period.