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目的: 探讨高血压病患者肺静脉血流(PVF) 频谱改变与心脏左室、右室功能的关系。方法: 用超声方法测量高血压病Ⅰ期组26 例、Ⅱ期组22例及20例正常对照组的心功能及PVF频谱参数并做比较。结果:高血压病Ⅰ期组及Ⅱ期组PVF频谱参数较对照组有显著差异(P< 0.05, 0.001), 且组间差异显著(P< 0.05); 高血压病各组E/A较对照组显著降低 (P< 0.05, 0.001), Ⅱ期组EF及Pa-v 较对照组差异显著(P均< 0.001), Ⅰ期组收缩功能参数较对照组差异不明显(P> 0.05); PVF频谱各参数与心脏功能参数相关分析表明,PVa及PVd 与ACT/RVET显著相关(r分别为- 0.87, 0.84), E/A与PVs/PVd 显著负相关(r= - 0.95)。结论: 高血压病患者左室及右室舒张功能均降低与高血压病程是递进关系,收缩功能改变在后期有所降低;肺静脉血流频谱对评价高血压病进程有参照意义, 特别是PVd降低, PVa增高敏感反映高血压病进程中右室后负荷的改变, 影响右室收缩功能
Objective: To investigate the relationship between changes of pulmonary venous flow (PVF) and left ventricle and right ventricle in hypertensive patients. Methods: 26 patients with stage Ⅰ hypertension, 22 stage Ⅱ and 20 normal controls were included in this study. The cardiac function and PVF parameters were compared by ultrasound. Results: There were significant differences in PVF spectrum parameters between hypertension group Ⅰ and group Ⅱ (P <0.05, 0.001), and there was significant difference between the two groups (P <0.05). Hypertension Group E / A was significantly lower than that of the control group (P <0.05, 0.001). There were significant differences in EF and Pa-v between the two groups (P <0.001), and the systolic function parameters The correlation between PVF parameters and cardiac function parameters showed that there was a significant correlation between PVa and PVd and ACT / RVET (r = -0.87 and 0.84, respectively), E / A had a significant negative correlation with PVs / PVd (r = - 0.95). Conclusion: The decrease of diastolic function of left ventricle and right ventricle in hypertensive patients is closely related to the course of hypertension, and the change of systolic function is reduced in the later period. The pulmonary venous flow spectrum has reference value for evaluating the progress of hypertension, especially PVd Reduce, PVa increased sensitivity to reflect the process of hypertension in the right ventricular afterload changes, affecting right ventricular systolic function