八、循环系统药类心得宁片及注射液,可引起剥脱性皮炎,苔癣样和红斑性皮疹、角质化皮癣、对称性角膜炎结膜炎、视力损害及肠梗阻等毒副反应。其它属于全身性损害的症状有耳聋、耳鸣、分泌性中耳炎、鼻和口腔粘膜的复发性溃疡,少数病例出现浆膜性损害—脑膜炎或坏死性腹膜炎,多数报道在用药一年以上,有时停药数月或几年后才出现这些病理变化,实际上常以皮肤 Eight, circulatory system medicine experience Ning tablets and injection, can cause exfoliative dermatitis, lichenoid and erythema rash, keratinized skin ringworm, symmetrical keratitis conjunctivitis, visual impairment and intestinal obstruction and other side effects. Other symptoms of systemic damage include deafness, tinnitus, otitis media with effusion, recurrent ulceration of the nose and oral mucosa, serosal damage in a few cases - meningitis or necrotizing peritonitis, most reported more than a year after treatment, and sometimes stopped These few months or years after the drug appears these pathological changes, in fact, often to the skin