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婴儿到达接种麻疹疫苗月龄时,常因一些禁忌证而推迟或错过免疫机会。作者在扎伊尔首都金沙萨给3.5和6月龄婴儿分别接种AIK-C、高滴度(EZ-H)和中等滴度(EZ-M)麻疹疫苗,观察他们在接种后0~15天内出现流涕、咳嗽、腹泻、发热、结膜炎、皮疹等症状与免疫应答的关系。接种EZ-H疫苗后6周,6月龄组的抗体阳转率比3.5月龄组高2~3倍。抗体水平≥200mIU者,在3.5月龄组仅有23%;而6月龄组则占60%,接种EZ-M者为39%。接
When a baby arrives at the age of months after receiving a measles vaccine, they often postpone or miss the immunization due to some contraindications. The authors vaccinated AIK-C, high-titer (EZ-H) and moderate-titer (EZ-M) measles vaccines in 3.5 and 6-month old infants in Kinshasa, Zaire, and observed that within 0-15 days after vaccination There runny nose, cough, diarrhea, fever, conjunctivitis, rash and other symptoms and immune response. 6 weeks after inoculation of EZ-H vaccine, antibody positive rate in 6-month-old group was 2-3 times higher than that in 3.5-month-old group. Antibody levels ≥ 200mIU were only 23% in the 3.5 month old group, 60% in the 6 month old group and 39% in the EZ-M group. Pick up