当前矽肺病的诊断主要依靠X线胸部照片,为了更好地诊断矽肺和判断药物的疗效,我们试图从生化方面寻找适当的辅助指标。根据以往研究工作的报导及我们动物实验的结果,我们对北京及湖南省接触石英粉尘的工人血清中溶菌酶及血兰蛋白的改变进行了一些调查研究,现将结果分别介绍在下面。一、溶菌酶(Lysozyme) 近年来关于矽肺发病的理论,有些学者(Allison 等1966)认为是石英粉尘被吸入肺以后,肺内有大量吞噬细胞增生,矽尘被吞噬细胞吞噬后,会使细胞内的溶酶体 The current diagnosis of silicosis mainly depends on the chest X-ray pictures, in order to better diagnose the silicosis and determine the efficacy of drugs, we try to find the appropriate biochemical indicators. Based on the reports of previous studies and the results of our animal experiments, we conducted some investigations into the changes of lysozyme and hesium protein in the serum of workers exposed to quartz dust in Beijing and Hunan Provinces. The results are presented below. First, lysozyme (Lysozyme) In recent years the theory of silicosis, some scholars (Allison et al 1966) that quartz dust is inhaled into the lungs, the lungs have a large number of phagocytic cells, phagocytosis of silica dust will make the cells Within the lysosome