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本文报道我院自1963年7月~1990年10月收治子宫内膜间质肉瘤26例,占同期女性生殖肿瘤0.19%,其中低度恶性者22例,高度恶性者4例。此类肿瘤临床诊断较困难随病理类型的不同,恶性程度预后悬殊较大。本组术前确诊仅8例占30.8%,主要依靠术后病理诊断。由于该肿瘤少见,其命名也不统一,本文就肿瘤命名及组织学诊断进行了讨论,对本病的治疗以手术为主,Ⅰ~Ⅱ期患者应作广泛性全子宫加盆腔淋巴结清除术,并配合化疗,放疗及孕激素治疗可取得较好的疗效;对复发患者如能及时发现正确处理,采用化疗、放疗配合孕激素治疗仍可有良好疗效。患者三年,五年生存率分别为58.3%及47.6%。
This article reports from our hospital from July 1963 to October 1990, 26 cases of endometrial stromal sarcoma, accounting for 0.19% of female reproductive tumors over the same period, of which 22 cases of low-grade malignant, 4 cases of highly malignant. The clinical diagnosis of these tumors is more difficult with the different types of pathology, malignant prognosis greater disparity. The preoperative diagnosis of only 8 cases accounted for 30.8%, mainly by postoperative pathological diagnosis. Due to the rare tumor, its name is not uniform, this article on the tumor nomenclature and histological diagnosis were discussed, the treatment of this disease to surgery, Ⅰ ~ Ⅱ patients should be extensive uterine and pelvic lymph node dissection, And with chemotherapy, radiotherapy and progesterone treatment can achieve better efficacy; recurrence of patients such as timely detection of correct treatment, the use of chemotherapy, radiotherapy with progesterone treatment can still have a good effect. Three years of patients, five-year survival rates were 58.3% and 47.6%.