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在感觉神经传导速度逆向检查法中,取电极间距为4cm常可获得最大感觉动作电位振幅,但尚缺乏生理学的基础研究。 Stolov曾认为,如果神经传导速度是50m/s,而神经膜表面的单个动作电位时程是0.8ms,从理论推算出最大去极化范围应是4cm(50m/s=L/0.8ms)。如果神经传导速度是40m/s,则适宜的电极间距将是3.2cm。神经动作电位的时程是随着神经的生理状态而变化的,神经细胞膜上动作电位的传播也受许多因素的影响,包括轴突直径、髓鞘是否完整、体温、年龄和不应期等。神经动作电位峰时程和绝对不应期大致相近,约为0.4ms~1.0ms,绝对不应期随温度下降而延长,如果绝对不应期延长,神经动作电位出现的频率减少,动作电位的传导速度也将变慢。
Sensory nerve conduction velocity in the reverse examination, taking the electrode spacing of 4cm can often get the maximum sense of action potential amplitude, but the lack of basic physiological research. Stolov once thought that if the nerve conduction velocity is 50 m / s and the single action potential duration on the surface of the neural membrane is 0.8 ms, the theoretical maximum depolarization range should be 4 cm (50 m / s = L / 0.8 ms). If the nerve conduction velocity is 40 m / s, then the appropriate electrode spacing will be 3.2 cm. The time course of nerve action potential changes with the physiological state of nerve. The transmission of action potential on nerve cell membrane is affected by many factors, such as axonal diameter, integrity of myelin, body temperature, age and refractory period. Nerve action potential peak duration and absolute refractory period is approximately similar, about 0.4ms ~ 1.0ms, the absolute refractory period with the temperature decline and prolongation, if the absolute refractory period, the frequency of the occurrence of the nerve action potential decreases, the action potential The conduction speed will also slow down.