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高血压为动脉粥样硬化的重要促发因素,与心肌梗塞的发病有密切关系。根据北京、上海地区的统计资料,冠心病中有62.9~93.1%的病人有高血压史,心肌梗塞病人中有60~68%伴发或发病前伴有高血压。高血压病人一旦发生心肌梗塞,大部分血压发生不同程度的下降;但仍有一部人血压持续性增高。这必然要加重心脏的负荷,增加心肌耗氧量,甚至要导致梗塞面积扩大,及诱发左心衰。一般认为动脉收缩压在160毫米汞柱以上就应该进行降压治疗,使收缩压较原水平下降20~40毫米汞
Hypertension is an important contributing factor of atherosclerosis, and the incidence of myocardial infarction are closely related. According to statistics in Beijing and Shanghai, 62.9-93.1% of patients with coronary heart disease have a history of hypertension, and 60-68% of patients with myocardial infarction have concomitant or pre-morbid hypertension. In hypertensive patients, myocardial infarction occurred, most of the blood pressure decreased to varying degrees; but there is still a sustained increase in blood pressure. This is bound to increase the load on the heart, increase myocardial oxygen consumption, and even lead to an enlarged infarct size, and induced left heart failure. Generally believed that arterial systolic blood pressure in the 160 mm Hg above should be antihypertensive treatment, the systolic blood pressure decreased by 20 to 40 mm Hg