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移植物抗白血病作用(GVL)是异基因造血干细胞移植后,引起造血系统肿瘤持续缓解状态的一种免疫介导的反应。目前,对GVL的机理仍不清楚。临床上观察到,在GVL出现前,病人多经历了一个急或慢性的移植物抗宿主病(GVHD)过程。GVHD使受者正常的组织和细胞受到损伤,而同时产生
Graft-versus-leukemia (GVL) is an immune-mediated response to hematopoietic system tumors that persist after allogeneic hematopoietic stem cell transplantation. At present, the mechanism of GVL is still not clear. Clinically, patients experienced an acute or chronic graft-versus-host disease (GVHD) process more frequently before the appearance of GVL. GVHD causes normal tissues and cells of the recipient to be damaged while being produced