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心脉通片由毛冬青、当归、丹参、三七等中药组成。本实验用兔颈动脉血栓模型观察其对动脉性血栓的影响,用玻片法观察其对凝血时间的影响。实验结果显示,心脉通片分两个计量组558、1118mg/kg连续三天灌胃给药,其血栓湿重分别为9.54±3.68mg、6.32±2.98mg,较生理盐水组(16.69±4.09mg)明显减轻(p<0.01),心脉通片的凝血时间分别为335±44sec、386±39sec,较生理盐水组(158±21sec)亦明显延长(p<0.01)。表明心脉通片能抑制动脉血栓形成和延长凝血时间。
Xinmaitong tablets consist of Maodongqing, Angelica, Salvia miltiorrhiza and Panax notoginseng. In this experiment, rabbit carotid artery thrombosis model was used to observe its effect on arterial thrombosis, and its effect on clotting time was observed by slide method. The experimental results showed that Xinmaitong tablets were administered by gavage for two consecutive days at 558 and 1118mg/kg in two measurement groups. The thrombus wet weights were 9.54±3.68mg and 6.32±2.98mg, respectively, which were higher than those of saline group (16.69±4.09). Mg) was significantly reduced (p<0.01), and the clotting times of Xinmai Tongtong were 335±44 sec and 386±39 sec, respectively, which was significantly longer than that of the normal saline group (158±21 sec) (p<0.01). It was shown that Xinmaitong can inhibit arterial thrombosis and prolong clotting time.