Immunomodulation effects of heat-treated Enterococcus faecalis FK-23(FK-23) in mice

来源 :Journal of Nanjing Medical University | 被引量 : 0次 | 上传用户:csc000000
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Objective:The purpose of this study was to evaluate the effects of Enterococcus faecalis FK-23(FK-23) on the immune function in mice. Methods:Mice were treated with three doses of the FK-23(0.05,0.1,0.2,0.6 g/kg body weight) for 30 days. Delayed type hypersensitivity (DTH),monocyte phagocytic function,serum hemolysis antibody and natural killer cell activity were studied. Results:The significant increases in mice treated with 0.6 g/kg bw were found in DTH,phagocytic function of monocyte,serum hemolysis antibody and natural killer cell activity. Conclusion:The results from the present study suggest that FK-23 could improve both specific and nonspecific immune function. Objective: The purpose of this study was to evaluate the effects of Enterococcus faecalis FK-23 (FK-23) on the immune function in mice. Methods: Mice were treated with three doses of the FK-23 (0.05,0.1,0.2, 0.6 g / kg body weight for 30 days. Delayed type hypersensitivity (DTH), monocyte phagocytic function, serum hemolysis antibody and natural killer cell activity were studied. Results: The significant increases in mice treated with 0.6 g / kg bw were found in DTH, phagocytic function of monocyte, serum hemolysis antibody and natural killer cell activity. Conclusion: The results from the present study suggest that FK-23 could improve both specific and nonspecific immune function.
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