滑石粉早已广泛用为片剂的润滑剂,由于它是一种天然产品,化学組成不恒定,常随其来源及制法而异。滑石粉是天然的透閃石等粉碎而成,一般組成为3MgO·4 SiO_2·H_2O,其中所含杂质則有碳酸鈣、硅酸鈣及氧化铁等。作者即研究各种滑石粉对阿司匹林片的稳定性产生何种不同的影响。試驗时制成三组阿司匹林片剂,第一组处方含有商品滑石粉A、B、C及D四种,第二組含有酸洗的滑石粉A、B、C及D,第三組合有滑石粉A并添加0.71毫 Talc has long been widely used as a tablet lubricant, because it is a natural product, the chemical composition is not constant, often depending on their sources and methods vary. Talc is a natural crushed tremolite made, generally composed of 3MgO 4 SiO 2 H 2 O, which contains impurities such as calcium carbonate, calcium silicate and iron oxide. The authors studied the different effects of various talc on the stability of aspirin tablets. Three aspirin tablets were made during the test. The first group contained four commercial talc powders A, B, C and D, the second contained the pickled talc powders A, B, C and D. The third group consisted of talc Powder A and add 0.71 milliliters