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目的观察口服红霉素对早产儿喂养不耐受的临床疗效。方法收集2006年1月—2008年12月的72例喂养不耐受的早产儿,随机分为治疗组36例和对照组36例。治疗组少食多餐、体位疗法等非药物治疗基础上给予口服红霉素[20mg/(kg.d)],对照组给予少食多餐、体位疗法等非药物治疗常规治疗,比较患儿在呕吐、体重增长等方面的情况。结果治疗组与对照组在呕吐症状消退、全胃肠道喂养日龄、体重增长二组比较差异有统计学意义(P<0.01)。结论口服红霉素治疗早产儿喂养不耐受是安全、有效的。
Objective To observe the clinical effect of oral erythromycin on intolerance in premature infants. Methods Seventy-two preterm infants with intolerance were collected from January 2006 to December 2008 and were randomly divided into treatment group (36 cases) and control group (36 cases). Oral erythromycin [20mg / (kg · d)] was given on the basis of non-drug therapy in the treatment group such as eating more meals and body position therapy. The control group was given routine treatment of non-drug therapy, such as eating less meals and body position therapy. , Weight gain and other aspects of the situation. Results There was significant difference between the two groups in the treatment group and the control group (P <0.01) in the regression of vomiting, total gastrointestinal feeding day and body weight gain. Conclusion Oral erythromycin treatment of premature infants intolerant is safe and effective.