妊娠急性脂肪肝是妊娠后期特有的疾病,1934年由stander 报道过1例,1940年sheehan 首先肯定其组织学改变,并命名为“产科急性黄色萎缩”。但这一病名易于同妊娠合并暴发型肝炎时的肝黄萎缩相混同,现在一般采用1956年由moore 提出的妊娠急性脂肪肝(AFLP)。过去认为AFLP为一罕见而致命的疾病,近年来由于提高了对本病的诊治水平,其发生率趋向增加,死亡率趋向下降,说明轻症病例许非少见,亦非致命。现结合文献概括如下。 Acute fatty liver of pregnancy is a peculiar disease of late pregnancy, reported by stander in 1934, 1 case, 1940 sheehan first affirmed the histological changes, and named as “obstetric acute yellow atrophy.” However, this disease is easily confused with liver atrophy during pregnancy complicated by fulminant hepatitis. Pregnancy-induced acute fatty liver (AFLP), proposed by Moore in 1956, is now commonly used. In the past, AFLP was considered as a rare and fatal disease. In recent years, due to the improvement of the diagnosis and treatment of this disease, the incidence of AFLP tends to increase and the mortality rate tends to decrease, indicating that mild cases are rare and not fatal. Now combined with the literature summarized as follows.