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约在50年前,Cuthbertson 描述了人体遭受损伤后呈现氮的过度丧失。由于伴有尿的变化,他认为这是因肌蛋白分解增加所致。肌酸和肌酐在当时被作为是尿内重要的肌肉标示物。锌以后才被采用。现认为3-甲基组氨酸(3-MeHis)是必须被应用的肌肉标
About 50 years ago, Cuthbertson described excessive loss of nitrogen after injury to the human body. He believes this is due to increased muscle proteolysis due to changes in urine. Creatine and creatinine were then used as important intramuscular markers of muscle. Zinc was adopted after. It is thought that 3-methylhistidine (3-MeHis) is a muscle marker that must be applied