目的研究蒙药多叶棘豆Oxytropis myriophy全草的化学成分。方法采用硅胶柱色谱、Sephadex LH-20柱色谱和薄层色谱等方法分离纯化,根据理化性质和波谱数据鉴定其结构。结果从多叶棘豆全草氯仿和醋酸乙酯萃取物分离得到11个化合物,分别鉴定为5-羟基-7,4′-二甲氧基黄酮(1)、4-羟基苯乙酮(2)、5,4′-二羟基-7,3′-二甲氧基黄酮(3)、5,7-二羟基-6,4′-二甲氧基黄酮(4)、异鼠李素(5)、山柰酚(6)、苯乙酮-4-O-β-D-葡萄糖苷(7)、2-羟基-6-甲氧基苯乙酮-4-O-β-D-葡萄糖苷(8)、6-甲氧基香豆素-7-O-β-D-葡萄糖苷(9)、异鼠李素-3-O-β-D-葡萄糖苷(10)、山柰酚-3-O-β-D-葡萄糖苷(11)。结论 11个化合物均首次从该植物中分离得到,其中化合物1、7、8为首次从棘豆属植物中分离得到。 Objective To study the chemical constituents of the whole plant Oxytropis myriophy. Methods The compounds were isolated and purified by silica gel column chromatography, Sephadex LH-20 column chromatography and thin layer chromatography. Their structures were elucidated on the basis of physico-chemical properties and spectral data. Results Eleven compounds were isolated from chloroform and ethyl acetate extract of Artemisia annua and identified as 5-hydroxy-7,4’-dimethoxyflavone (1), 4-hydroxyacetophenone ), 5,4’-dihydroxy-3,3’-dimethoxyflavone (3), 5,7-dihydroxy-6,4’-dimethoxyflavone (4), isorhamnetin 5), kaempferol (6), acetophenone-4-O-β-D-glucoside (7), 2-hydroxy-6-methoxyacetophenone-4-O-β-D-glucose (8), 6-methoxycoumarin -7-O-β-D-glucoside (9), isorhamnetin-3-O-β-D-glucoside (10) -3-O-β-D-glucoside (11). Conclusion All the 11 compounds were isolated from this plant for the first time. Compounds 1, 7 and 8 were isolated from Oxytropis for the first time.