近年来 ,血液净化在一些重症、难治性自身免疫性疾病(AD)的治疗中发挥了重要作用。1　血液净化疗法的作用机制血浆置换 (plasmapheresis ,PP)和免疫吸附 (immunoad sorption ,IA)是目前临床应用于AD的主要血液净化技术。1.1　PP　PP是指抽取患者血液后经血液置换机除去血浆或血 In recent years, blood purification has played an important role in the treatment of some severe and refractory autoimmune diseases (AD). 1 The mechanism of blood purification therapy Plasma exchange (plasmapheresis, PP) and immunoadsorption (IA) are the main blood purification technologies currently used clinically in AD. 1.1 PP PP refers to the removal of plasma or blood by blood replacement after the patient’s blood is drawn