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目的:探讨心房颤动(房颤)患者血清高敏C反应蛋白(hs-CRP)的变化,及与左房内径(LAD)的相关性。方法:选取房颤患者120例(持续性房颤组56例,阵发性房颤组64例),窦性心律者60例为对照组,采用超声心动图测量2组的LAD,免疫速率散射比浊法测定hs-CRP含量,并对结果进行相关分析。结果:持续性房颤组血清hs-CRP的水平显著高于阵发性房颤组和对照组,差异有统计学意义。而阵发性房颤组患者血清hs-CRP水平虽高于对照组,但差异无统计学意义。房颤组患者血清hs-CRP水平与LAD存在正相关关系。结论:持续性房颤患者hs-CRP增高,与LAD呈正相关。
Objective: To investigate the change of serum high-sensitivity C-reactive protein (hs-CRP) in patients with atrial fibrillation (AF) and the correlation with left atrium inner diameter (LAD). Methods: A total of 120 patients with atrial fibrillation (56 patients with persistent atrial fibrillation, 64 patients with paroxysmal atrial fibrillation) and 60 patients with sinus rhythm were selected as control group. Echocardiography was used to measure the LAD, Turbidimetric determination of hs-CRP content, and the results were analyzed. Results: The serum levels of hs-CRP in patients with persistent AF were significantly higher than those in patients with paroxysmal atrial fibrillation and controls. The difference was statistically significant. The serum hs-CRP levels in patients with paroxysmal atrial fibrillation were higher than the control group, but the difference was not statistically significant. The serum hs-CRP level in patients with AF was positively correlated with LAD. Conclusion: The hs-CRP increased in patients with persistent AF and positively correlated with LAD.