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多药耐药是肿瘤化疗的主要障碍,然而其形成机制非常复杂,单个耐药细胞可以同时具有多种抗药机制,而每个机制又可使肿瘤细胞对不同类型的抗肿瘤药产生多种耐药表型。现将肿瘤细胞多药耐药的研究进展简述如下。1多药耐药(MDR)与多药耐药基因(MDR1)和多药耐药相关蛋白(MRP)的关系?
Multidrug resistance is the main obstacle of tumor chemotherapy, however, its formation mechanism is very complex. Single drug resistant cell can simultaneously have multiple drug resistance mechanisms, and each mechanism can make tumor cells produce different types of anti-tumor drugs Resistance phenotype. Now the research progress of multidrug resistance of tumor cells is as follows. 1 multidrug resistance (MDR) and multidrug resistance gene (MDR1) and multidrug resistance protein (MRP) relationship?