缺血性脑卒中是一组临床症候群,主要表现为脑梗死、短暂性脑缺血发作(TIA),具有较高的病死率和致残率,对人类健康危害较大。本病的年复发率约为4%～14%,其中脑卒中后1年内的复发率约13%,此后4年,每年的复发率为4%[1]。他汀类药物作为羟基戊二酰辅酶A还原酶抑制剂,不仅是降脂药,而且在缺血性脑血管病二级预防中起重要作用。我所应用辛伐他汀对脑卒中二级预防疗效进行观察,现报道如下。 Ischemic stroke is a group of clinical syndromes, mainly manifested as cerebral infarction, transient ischemic attack (TIA), with high mortality and morbidity, human health hazards. The annual recurrence rate of the disease is about 4% to 14%, of which 1 year after stroke recurrence rate of about 13%, 4 years after the annual recurrence rate of 4% [1]. As a hydroxyglutaryl coenzyme A reductase inhibitor, statins are not only lipid-lowering drugs, but also play an important role in the secondary prevention of ischemic cerebrovascular disease. I applied simvastatin secondary prevention of stroke was observed, are reported below.