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作者对7例胸腺瘤(上皮细胞为主型6例,上皮细胞、淋巴细胞混合型1例)进行了6～34个月的追踪观察,择重于免疫偏向和自身免疫现象的检测。其中4例恶性浸润性胸腺瘤并发广泛严重的重症肌无力症和风湿性关节炎。另2例检测证明有自身免疫抗体(抗横纹肌和抗核抗体),临床则表现系统性红斑狼疮。此外多数病例外周血中T、B细胞绝对值低于正常
The authors followed up for 6 to 34 months in 7 patients with thymoma (epithelial cell predominance was 6, epithelial cell and lymphocyte mixed type 1), with emphasis on the detection of immune bias and autoimmunity. Four cases of malignant invasive thymoma complicated with extensive severe myasthenia gravis and rheumatoid arthritis. The other two tests showed that autoimmune antibodies (anti-striated and antinuclear antibodies), clinical manifestations of systemic lupus erythematosus. In addition, most cases of peripheral blood T, B cells absolute value is lower than normal