由于能及时发现和治疗心律失常,急性心肌梗塞的死亡率已降低。目前,对于能减少急性缺血性心肌损害的措施,应予以评价。作者用心肌梗塞的实验模型进行超微结构和生化方面的联合研究,证明溶酶体破裂与早期细胞损害相关。及早用药理剂量的甲基强的松龙可能使之改善。早期缺血时心脏中迅速发生之生化的、功能的、和结构方面 Due to the timely detection and treatment of arrhythmias, the mortality rate of acute myocardial infarction has been reduced. Currently, measures to reduce acute ischemic myocardial damage should be evaluated. The authors used a combination of ultrastructural and biochemical studies in experimental models of myocardial infarction, demonstrating that lysosomal rupture is associated with early cell damage. Early doses of methylprednisolone may improve it. The rapid biochemical, functional, and structural aspects of the heart during early ischemia