地特胰岛素治疗老年2型糖尿病患者的疗效评价

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目的 比较口服降糖药(OAD)血糖控制不佳的老年T2DM患者加用地特胰岛素、甘精胰岛素或中性鱼精蛋白锌胰岛素(NPH)的疗效和安全性.方法 将130例OAD血糖控制不佳的老年T2DM患者随机分为观察组和对照组.观察组给予地特胰岛素治疗,对照组给予甘精胰岛素治疗.治疗12周后评价2组患者的临床疗效.结果 2组治疗后FBG、2hPG、HbA1C水平均较同组治疗前明显降低(P<0.05),但观察组与对照组比较差异无统计学意义(P>0.05);观察组体质量指数(BMI)低于对照组,差异有统计学意义(P<0.05)
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