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目的：检测２－乙酰氨基芴等１５种不同结构类型和作用机制的诱变剂和环磷酰胺、丝裂霉素Ｃ等１４种抗肿瘤药，以及黄酮类药物ＳＩＰＩ－５４９、ＳＩＰＩ－６４４等３３种化合物对小鼠的遗传毒性。方法：大肠杆菌ｒｅｃＡ／ｕｖｒＢ宿主中介差异性ＤＮＡ修复试验（Ｅ．ｃｏｌ
OBJECTIVE: To detect 15 kinds of mutagens, such as 2-acetylaminofluorene, and 14 kinds of antineoplastic agents such as cyclophosphamide and mitomycin C, as well as flavonoids SIPI-549 and SIPI-644 Genotoxicity of 33 compounds in mice. Methods: Escherichia coli recA / uvrB host mediator DNA repair test (E.col