肠道病毒71型(enterovirus 71,EV71)属小RNA病毒科肠道病毒属,主要引起手足口病(hand-foot-and-mouth disease,HFMD)和中枢神经系统疾病。1969年在美国加里福尼亚分离出首株EV71[1]。近年来EV71在亚太地区持续流行[2-9],特别是1998 Enterovirus 71 (EV71) belongs to the genus Picornavirus and causes mainly hand-foot-and-mouth disease (HFMD) and central nervous system diseases. In 1969 in California, the United States isolated the first EV71 [1]. In recent years, EV71 continues to prevail in the Asia-Pacific region [2-9], especially in 1998