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观察肾功能、肾皮质、红细胞超氧化物歧化酶（SOD）、血浆过氧化脂质（LPO）、残肾形态学等指标，发现黄丹胶囊可以延缓5／6肾切除大鼠血尿素氮（BUN）、血肌酥（Scr）增高［黄丹胶囊（8．82mg／kg）组BUN（12．51±3．54）mmol／L，Scr（16．81±30．37）μmol／L；覆醛氧化淀粉组BUN（18．18±3．85）mmol／L，Scr（217．34±41．61）μmol／L］（P＜0．001），提高肾皮质、红细胞SOD（P＜0．01），降低血浆LPO（P＜0．01），延缓肾脏病理改变，从而延缓慢性肾衰的进程。
Observe the renal function, renal cortex, red cell superoxide dismutase (SOD), plasma lipid peroxide (LPO), residual kidney morphology, and other indicators and found that Huangdan Capsule can delay blood urea nitrogen in 5/6 nephrectomized rats ( BUN) and serum creatinine (Scr) increased [BUN (12.51±3.54) mmol/L in Huangdan capsule (8.82mg/kg) group, Scr (16.81±30.37) μmol/L; The aldehyde-oxidized starch group had BUN (18.18±3.85) mmol/L, Scr (217.34±41.61) μmol/L] (P<0.001), and increased renal cortex and red blood cell SOD (P< 0.01), decreased plasma LPO (P<0.01), delayed renal pathological changes, and thus delayed the progression of chronic renal failure.