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自从2009年3月墨西哥暴发甲型H1N1流感(甲流)以来,全球流感病例持续上升。人群对这种新型流感病毒普遍易感。根据临床症状体征和应用实时反转录聚合酶链技术(RT-PCR)在疑似病例的呼吸道分泌物标本中检测出甲流RNA可快速确诊甲流;一些抗甲流药物(如奥司他韦)亦取得良好的效果。根据其流行病学特点,冬春季节可能有更大规模的感染流行;就目前资料显示本次甲流与1918年至1920年暴发的西班牙流感相比致死率低。但担心的是这种新型甲流有变异的可能,一旦病毒变异会给中国乃至世界一个更大的挑战。本文以本次甲流的基础与临床为中心做一综述。
Since the outbreak of Influenza A (H1N1) in Mexico in March 2009, the number of global flu cases has continued to rise. The crowd is generally susceptible to this new flu virus. According to clinical signs and symptoms and the application of real-time reverse transcription-polymerase chain reaction (RT-PCR) in a suspected case of respiratory secretions samples detected in a flow of RNA can be quickly diagnosed with a flow; some anti-influenza drugs (such as oseltamivir ) Also achieved good results. According to its epidemiological characteristics, there may be a greater epidemic of infection in winter and spring; the current data indicate that this A-lethality is lower than that of the Spanish flu outbreak from 1918 to 1920. However, it is feared that this new type of H1N1 virus may have the possibility of mutation. Once the virus mutation, it will give China and even the world a bigger challenge. This article reviews the basic and clinical aspects of this flow.