早产仍然是婴儿围产期死亡的一个最重要原因,与早产有关的一个主要问题是绒毛膜羊膜炎,此病可导致母婴严重的后遗症,其检测手段还不尽人意.胎盘多形核白细胞浸润是绒毛膜羊膜炎的特点之一.IL-8对中性粒细胞有激活和炎性趋化作用.调查了患绒毛膜羊膜炎的早产儿,以确定胎儿期对感染该病所产生的内毒素刺激是否活跃产生IL-8. Preterm birth is still one of the most important causes of perinatal death in infants and one of the major problems associated with preterm birth is chorioamnionitis, which can lead to serious sequelae in infants and young children, and the detection of which is not satisfactory.Pplacental polymorphonuclear leukocytes Infiltration is one of the characteristics of chorioamnionitis .IL-8 on the activation of neutrophils and chemotaxis chemokines.Investigated the risk of chorioamnionitis in preterm children to determine the fetal period of infection caused by the disease Whether endotoxin stimulation is active produces IL-8.