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目的 观察右旋糖酐 40和聚维酮碘预防腹腔海水浸泡伤术后肠粘连的效果。方法 建立腹腔海水浸泡伤动物模型 ,观察对照组、右旋糖酐 40组、聚维酮碘组及右旋糖酐 40加聚维酮碘组处理术后肠粘连发生率的变化。结果 右旋糖酐 40组和聚维酮碘组动物术后肠粘连发生率显著低于对照组(P<0 .0 5 ) ,而右旋糖酐 40与聚维酮碘组术后肠粘连发生率显著低于以上三组 (P<0 .0 5 )。结论 右旋糖酐 40与聚维酮碘有减轻机体腹腔海水浸泡伤术后肠粘连发生的作用 ,二者合用能协同减轻机体术后肠粘连的发生
Objective To observe the effect of dextran 40 and povidone iodine on preventing intestinal adhesion after abdominal water immersion injury. Methods The animal models of water instillation in the peritoneal cavity were established. The incidence of intestinal adhesion was observed in 40 cases of control group, dextran 40, povidone-iodine group and 40 dextran-treated dextran group. Results The incidence of postoperative intestinal adhesion in dextran 40 and povidone-iodine groups was significantly lower than that in the control group (P <0.05), while the incidence of postoperative intestinal adhesion was significantly lower in dextran 40 and povidone-iodine groups Three groups (P <0.05). Conclusions Dextran 40 and Povidone iodine can reduce the occurrence of intestinal adhesion after abdominal water inoculation in sea celiac disease. The combination of the two can reduce the occurrence of intestinal adhesion after operation