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目的观察丹红注射液治疗急性ST段抬高型心肌梗死合并心力衰竭的疗效。方法 82例急性ST段抬高型心肌梗死合并心力衰竭患者,随机分成观察组(42例)和对照组(40例),观察组在行常规治疗的基础上静脉滴注丹红注射液;对照组单纯采用常规治疗。比较两组治疗前后的心功能变化和临床疗效。结果治疗前,两组心功能比较差异无统计学意义(P>0.05);经过治疗,两组心功能均明显改善,且观察组优于对照组,差异具有统计学意义(P<0.05)。观察组和对照组临床总有效率分别为95.24%、80.00%,差异具有统计学意义(P<0.05)。结论丹红注射液通过降低左心室舒张末期容积(LVEDV)、左心室收缩末期容积(LVESV)和左室射血分数(LVEF)来改善心肌缺血情况和心功能,在急性ST段抬高型心肌梗死合并心力衰竭的治疗中获得了良好的临床疗效,可在临床治疗中推广使用。
Objective To observe the effect of Danhong injection in treating acute ST-segment elevation myocardial infarction complicated with heart failure. Methods 82 patients with acute ST-elevation myocardial infarction complicated with heart failure were randomly divided into observation group (n = 42) and control group (n = 40). The observation group was given intravenous infusion of Danhong injection on the basis of routine treatment. Group using simple treatment. The changes of cardiac function and clinical efficacy before and after treatment were compared between the two groups. Results Before treatment, there was no significant difference in cardiac function between the two groups (P> 0.05). After treatment, the cardiac function of the two groups were significantly improved, and the observation group was better than the control group (P <0.05). The total effective rate of observation group and control group was 95.24% and 80.00%, respectively, with significant difference (P <0.05). Conclusion Danhong injection can improve myocardial ischemia and cardiac function by decreasing left ventricular end-diastolic volume (LVEDV), left ventricular end-systolic volume (LVESV) and left ventricular ejection fraction (LVEF) Myocardial infarction with heart failure treatment has been a good clinical efficacy, can be used in clinical treatment.