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目的探讨沂南地区妊娠期妇女TORCH感染与不良妊娠结局的关系,了解TORCH-IgM感染对孕妇妊娠不良结局的影响。方法采用酶联免疫吸附试验(ELISA)检测方法,通过对孕期发生不良妊娠的466例妇女来站做TORCH四项病原体血清学检测分析,随机抽取同期来站做围产期保健的正常妊娠的妇女466例作为对照组。结果不良妊娠孕妇的TOX-IgM、RV-IgM、CMV-IgM、HSVⅡ-IgM阳性率均明显高于正常妊娠的妇女(P<0.01)。结论 TORCH感染是导致孕妇不良妊娠结局的重要原因之一。因此对有生育计划的育龄妇女孕前进行TORCH-IgM检测是非常有必要的,对检测出TORCH阳性的高危人群采取积极治疗、跟踪随访、优生指导等综合管理措施,能明显降低宫内感染和胎、婴儿传播的机会,提高出生人口素质。
Objective To investigate the relationship between TORCH infection and adverse pregnancy outcomes in pregnant women in Yinan area and to understand the influence of TORCH-IgM infection on the adverse pregnancy outcomes in pregnant women. Methods Serological tests of four pathogens in TORCH were performed by using 466 pregnant women with unwanted pregnancies by enzyme-linked immunosorbent assay (ELISA), and randomly selected women with normal pregnancy as perinatal care during the same period 466 cases as a control group. Results The positive rates of TOX-IgM, RV-IgM, CMV-IgM and HSVⅡ-IgM in adverse pregnant women were significantly higher than those in normal pregnant women (P <0.01). Conclusion TORCH infection is one of the important causes of adverse pregnancy outcomes in pregnant women. Therefore, it is very necessary to test TORCH-IgM before pregnancy for pregnant women of childbearing age with fertility program. The comprehensive management measures such as active treatment, follow-up follow-up and eugenics guidance can significantly reduce intrauterine infection and fetal , Opportunities for infant transmission, and improving the quality of the birth population.