作者复习1948～1976的英文文献,其中32篇为急性心肌梗塞病人在住院期间曾用抗凝治疗作为治疗的一个项目,共15,978病例。此32篇均包括有仅用少量或不用抗凝剂的对照组。病例数少于30例者均予删除。抗凝治疗方法为单独用香豆素或印双酮衍化物,肝素加用香豆素或印双酮衍化物;或单独用肝素。结果显示,在18篇从病史挑选对照的非随机性对照研究中,15篇显示抗凝者的总死亡率及晚期病死率小于对照者;8篇交替对 The authors reviewed the English literature from 1948 to 1976, of which 32 were used as anticoagulant therapy for patients with acute myocardial infarction during hospitalization for a total of 15,978 cases. All 32 articles included a control group with little or no anticoagulant. Less than 30 cases were deleted. The anticoagulant therapy is coumarin or melezidone alone, heparin plus coumarin or melezidone derivatized, or heparin alone. The results showed that of the 18 non-randomized controlled trials selected from the medical history, 15 showed that the total mortality rate and the late mortality rate of anticoagulants were less than those of the control subjects. Eight alternating