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目的分析外周原始神经外胚层肿瘤(pPNET)的CT和MR I表现,以期提高对该病的认识。方法回顾性分析6例经病理诊断的外周原始神经外胚层肿瘤的CT和MR I表现。男4例,女2例,其中起源于骨组织2例,软组织pPNET 4例。结果骨组织pPNET表现为溶骨性骨质破坏伴有软组织肿块,病灶CT呈等密度,MR I T1W I等信号,T2W I等、高信号,增强明显但不规则,无明显瘤骨和骨膜反应;软组织pPNET病灶体积比较大,直径>6 cm,CT等密度,MR I T1W I等、低信号,T2W I等、高信号,增强明显,对周围正常组织有侵袭,无钙化。2例有明显的坏死。结论pPNET的CT和MR I表现缺乏特征性,但有助于本病良恶性鉴别、判断手术可切除性、检出远处转移和评价治疗效果。
Objective To analyze the CT and MRI features of peripheral primitive neuroectodermal tumors (pPNET) in order to improve their understanding of the disease. Methods The CT and MRI findings of 6 cases of peripheral primitive neuroectodermal tumors diagnosed by pathology were retrospectively analyzed. 4 males and 2 females, of which 2 cases originated in bone tissue, 4 cases of soft tissue pPNET. Results The pPNET of osteoporotic tissue showed osteolytic osteoclasts with soft tissue mass. The CT of the lesion showed isodense density, MR I T1W I signal and T2W I high signal, which were obviously but irregularly increased without significant tumor and periosteal reaction The volume of pPNET lesions in soft tissue was relatively large, with a diameter of> 6 cm. CT density, MR I T1W I, low signal and T2W I increased the signal intensity and obviously affected the surrounding normal tissues without calcification. 2 cases had obvious necrosis. Conclusion The CT and MRI features of pPNET lacks characteristic features, but it is helpful to differentiate the benign and malignant lesions, to determine the resectability, to detect distant metastasis and to evaluate the therapeutic effect.