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目的研究广东省接触猪职业人群携带抗猪流感病毒抗体情况,为及时预警和防控新型流感病毒从猪到人的传播提供科学依据。方法随机选取广东省内5个地级市(广州、中山、清远、江门和佛山)的5个屠宰加工场和10个猪养殖场的接触猪职业人群作为调查对象,采用血凝抑制试验检测血清中抗猪H1、H3、H4和H9等4种猪流感病毒抗体。结果共检测职业人群血清样本354份,检出抗猪H1、H3亚型抗体阳性218份,总阳性率为61.58%;其中抗猪H1抗体阳性率为8.76%,抗猪H3抗体阳性率为52.82%,两者差异有统计学意义(P<0.01);未检出抗猪H4和H9亚型抗体阳性者。养殖、屠宰、检疫及后勤这3类不同工种人群的抗猪H1抗体和抗猪H3抗体阳性率差异均无统计学意义(均P>0.05)。结论广东省接触猪职业人群普遍携带抗猪流感病毒抗体,应长期开展对该人群的流感病毒血清学监测,及时预警和防控新型流感病毒由猪向人的传播。
Objective To study the status of anti-swine influenza virus antibody in the exposed pig population in Guangdong Province and provide a scientific basis for early warning and prevention and control of the spread of new influenza virus from pig to human. Methods Five occupational groups exposed to pigs from 5 slaughter and processing plants and 10 pig farms in 5 prefecture-level cities (Guangzhou, Zhongshan, Qingyuan, Jiangmen and Foshan) in Guangdong Province were selected as the survey subjects. Serum levels were determined by hemagglutination inhibition test Anti-swine H1, H3, H4 and H9 and other four kinds of swine flu antibodies. Results A total of 354 serum samples from occupational groups were detected. The positive rate of anti-swine H1 and H3 subtype antibodies was 218.5%, and the positive rate of anti-swine H1 antibody was 8.76% and the positive rate of anti-swine H3 antibody was 52.82 %, The difference between the two was statistically significant (P <0.01); anti-H4 antibody and H9 subtype antibodies were not detected. There was no significant difference in the positive rates of anti-swine H1 antibody and anti-swine H3 antibody among the three different types of farming, breeding, slaughtering, quarantine and logistics groups (all P> 0.05). CONCLUSION: Anti-swine influenza virus antibodies are commonly carried in occupational groups exposed to pigs in Guangdong Province. Serological surveillance of influenza virus in this population should be carried out for a long period of time to timely warn and prevent and control the spread of novel influenza viruses from pigs to humans.