观察了国产氨苄青霉素与舒巴坦合剂（舒氨新）治疗７２例腹腔及胆系感染的疗效。分离出的２４株病原菌中２２株产生β－内酰胺酶，对氨苄青霉素的耐药率高达８３．３％，而对舒氨新则仅２株耐药７２例患者经舒氨新治疗后１９例痊愈，总有效率为９３．１％，说明β－内酰胺酶介导的耐药能被β－内酰胺酶抑制剂舒巴坦所抑制。舒氨新在胆汁中的高浓度亦有助于提高疗效。 To observe the efficacy of domestic ampicillin and sulbactam combination (Shu Amin) in the treatment of 72 cases of abdominal and gall bladder infection. Among the 24 isolates isolated, 22 strains produced β-lactamase, the resistance rate to ampicillin was as high as 83.3%, while only 2 strains were resistant to sulamon to 72 patients after resveratrol treatment The cases were cured, the total effective rate was 93.1%, indicating β-lactamase-mediated resistance can be β-lactamase inhibitor sulbactam inhibition. Shu ammonia new high concentration in the bile also helps to improve the efficacy.