Eco-friendly synthesis of 2-substituted-2,3-dihydro-4(1H)-quinazolinones in water

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2-Substituted-2,3-dihydro-4(1H)-quinazolinones were synthesized in high yield by condensation of 2-anthranilamide with aromatic aldehydes or ketones in refluxing water without catalyst. This protocol has advantages of high yield, simple work-up and environmental friendly procedure.
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