三维适形放疗和调强放疗治疗原发性鼻咽癌的剂量学对比研究:来自埃及的经验报道(英文)

来源 :Chinese-German Journal of Clinical Oncology | 被引量 : 0次 | 上传用户:yellue
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Objective: The study is a comparative study, the aim of which is to compare 3D conformal radiation therapy (3D-CRT) and intensity modulated radiation therapy (IMRT) in treating nasopharyngeal carcinomas; dosimetrically evaluating and comparing both techniques as regard target coverage and doses to organs at risk (OAR). Methods: Twenty patients with nasopharyngeal carcinoma were treated by 3D-CRT technique and another 20 patients were treated by IMRT. A dosimetric comparison was done by performing two plans for the same patient using Eclipse planning system (version 8.6). Results: IMRT had a better tumor coverage and conformity index compared to 3D-CRT plans (P value of 0.001 and 0.004), respectively. As for the dose homogeneity it was also better in the IMRT plans and the reason for this was attributed to the dose inhomogeneity at the photon/electron junction in the 3D-CRT plans (P value 0.032). Also, doses received by the risk structures, particularly parotids, was significantly less in the IMRT plans than those of 3D-CRT (P value 0.001). Conclusion: IMRT technique was clearly able to increase the dose delivery to the target volume, improve conformity and homogeneity index and spare the parotid glands in comparison to 3D-CRT technique. Objective: The study is a comparative study, the aim of which is to compare 3D conformal radiation therapy (3D-CRT) and intensity modulated radiation therapy (IMRT) in treating nasopharyngeal carcinomas; dosimetrically evaluating and comparing both techniques as regard target coverage and doses to organs at risk (OAR). Methods: Twenty patients with nasopharyngeal carcinoma were treated by 3D-CRT technique and another 20 patients were treated by IMRT. A dosimetric comparison was done by performing two plans for the same patient using Eclipse planning system (version 8.6). Results: IMRT had a better tumor coverage and conformity index compared to 3D-CRT plans (P value of 0.001 and 0.004), respectively. As for the dose homogeneity it was also better in the IMRT plans and the reason for this was attributed to the dose inhomogeneity at the photon / electron junction in the 3D-CRT plans (P value 0.032). Also, doses received by the risk structures, particularly parotids, was significantly less in the IMRT plans than those of 3D-CRT (P value 0.001). Conclusion: IMRT technique was clearly able to increase the dose delivery to the target volume, improve conformity and homogeneity index and spare the parotid glands in comparison to 3D-CRT technique .
其他文献
The Ethernet passive optical network(EPON) is the next generation of broad-band network technique.A crucial issue in EPONs is the sharing of uplink bandwidth am
  物理量指数是强对流天气监测分析、机理研究和预报预警的重要手段之一,但大多数指数都是针对平原地区雷暴发生的环境特点而设计的,不能在高原地区直接应用,或应用效果不好。
frank02082最近在网上看到许多M&K的介绍,据说许多大的电影公司、录音室使用他们的产品,并且以后HI-FI也将是AC-3/DTS音效。我是初烧,请问作为第一套HI-FI器材,应购置整套影
苏联偉大的生理学家巴甫洛夫在研究高級神經活动时,特別注意保护性抑制的作用,他認为由于保护性抑制的發生可使神經細胞免于因过度的刺激而引起疲劳和耗損。在發生保护性抑
  本文通过对凉山州17个县市1971~2010年近40年气象整编资料的统计与分析,发现凉山州的暴雨有明显的地域和年、月、季分布特征,降雨次数也呈现明显的波动;凉山州南部多于北部,东
近年来,高血压治疗提倡非药物性疗法(静默疗法、运动、体重和食盐控制)。这些疗法有效的话,可避免药物引起公认的短期和未知的长期危险与副作用,尤其对许多药物治疗证明无益
服装配色三法山东胶南市工商局邮政编码:266400庄奎太当你身穿服装走在大街上,它给人们的第一个印象是色彩。色彩在人类生活中起着重大作用,人生来就喜欢色彩。在现代生活中,色、形、质
  利用常规、自动气象站、NCEP/NCAR再分析资料(1°×1°,逐6h)和WRF模式逐小时资料,对2010年6月30日—7月2日山东省暴雨过程的落区进行了分析.结果表明:本次暴雨过程具有暖区
会议
  华南地处低纬,由于受到西风带和热带系统共同影响,地形复杂,海陆热力差异较大,经常伴有近圆形结构的中尺度对流复合体(MCC)生成发展,常带来暴雨和强对流天气.通常,其发展
会议
目的:观察清热愈疡汤坐浴联合马应龙麝香痔疮膏治疗肛周湿疹的疗效.方法:选取2018年10月-2020年1月我院收治的104例肛周湿疹患者为研究对象,按照随机数字表法分为研究组和对