一、引言有机磷杀虫剂1605、1059等虽然对害虫的防治效果很高,但对人及高等动物也有剧毒作用,在应用时势必受到一定的限制,目前国际上的研究趋势是合成对人畜安全的有机磷和其他药剂,如甲基1605、甲基1059、馬拉賽翁,敌百虫、M—74与西米脫(Thimet)等的合成都是朝着这个方向努力的,但这些化合物不是对害虫毒力远較1605等为小,就是对人畜的毒力仍然很大, I. INTRODUCTION Although organophosphate insecticides such as 1605, 1059 and so on have a very high effect in controlling pests, they also have a high toxic effect on humans and higher animals and are bound to be limited in application. At present, the international trend is to synthesize Organophosphate and other pharmaceuticals for human and livestock safety, such as methyl 1605, methyl 1059, malathion, trichlorfon, M-74 and Thimet, all work in this direction These compounds are not virulent far more than 1605 and other small, that is, the virulence of humans and animals is still large,