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[目的]探讨茵栀黄注射液与丙谷胺联合应用治疗肝细胞性黄疸的临床疗效。[方法]肝细胞性黄疸80例,随机分为治疗组和对照组,治疗组42例,对照组38例,两组均给予保肝、支持、输液等治疗,同时治疗组采用茵栀黄注射液30 ml加入5％葡萄糖注射液250 ml中静脉滴注,1次／d;丙谷胺1 g,2次／d,口服,2周为1个疗程。2周后评估临床症状及复查血总胆红素水平。[结果]治疗后治疗组总有效率明显高于对照组(90.5％、68.4％,P<0.05);血总胆红素水平均明显好转[(53.1±22.4)、(110.8±41.2)mmol／L,P<0.05]。[结论]茵栀黄注射液与丙谷胺联合应用对肝细胞性黄疸有较好疗效。
[Objective] To explore the clinical effect of Yinzhihuang injection combined with proglumide in the treatment of hepatocellular jaundice. [Methods] 80 patients with hepatocellular jaundice were randomly divided into treatment group and control group, 42 cases in the treatment group and 38 cases in the control group. Both groups were given hepatoprotective, supportive, infusion and other treatment. Yinzhihuang injection Liquid 30 ml added 5% glucose injection 250 ml intravenous infusion, 1 / d; valproate 1 g, 2 times / d, orally, 2 weeks for a course of treatment. Two weeks later, the clinical symptoms and blood total bilirubin levels were evaluated. [Results] The total effective rate of the treatment group was significantly higher than that of the control group (90.5%, 68.4%, P <0.05); the levels of total bilirubin were significantly improved [(53.1 ± 22.4), (110.8 ± 41.2) mmol / L, P <0.05]. [Conclusion] Yinzhihuang injection combined with proglumide has a good curative effect on hepatocellular jaundice.