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目的观察阿托伐他汀治疗心肌梗死后无症状心力衰竭的疗效。方法 68例心肌梗死患者,随机分为观察组和对照组,每组34例。两组均给予常规治疗,观察组在常规治疗基础上加服阿托伐他汀。6个月后检测患者血清脑钠素(BNP)水平,检查心功能指标[左室射血分数(LVEF)、左室收缩末期内径(LVESD)、左室舒张末期内径(LVEDD)],测量6分钟步行距离。结果治疗后,观察组BNP水平明显低于对照组(P<0.05);观察组LVEF、LVESD、LVEDD心脏超声指标优于对照组(P<0.05);观察组6分钟步行距离明显长于对照组(P<0.05)。结论阿托伐他汀对改善心肌梗死后心功能疗效显著,值得临床推广。
Objective To observe the effect of atorvastatin on asymptomatic heart failure after myocardial infarction. Methods 68 patients with myocardial infarction were randomly divided into observation group and control group, 34 cases in each group. Both groups were given routine treatment, the observation group on the basis of conventional treatment plus atorvastatin. Six months later, the level of serum brain natriuretic peptide (BNP) was measured and the cardiac function indexes (left ventricular ejection fraction, left ventricular end-diastolic diameter, left ventricular end-diastolic diameter, LVEDD) Minutes walking distance. Results After treatment, the level of BNP in the observation group was significantly lower than that in the control group (P <0.05). The cardiac indexes of LVEF, LVESD and LVEDD in the observation group were better than those in the control group (P <0.05). The walking distance in the observation group was significantly longer than that in the control group P <0.05). Conclusion Atorvastatin has a significant effect on improving cardiac function after myocardial infarction, which is worthy of clinical promotion.