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美国儿科学会传染病委员会最近发布了一项关于细菌性脑膜炎患儿使用地塞米松的新建议。现节录于下: 一、地塞米松很可能减轻流感嗜血杆菌脑膜炎导致耳聋的可能性,尽管在可以作出绝对性的推荐之前还需要进行另外一些安慰剂对照研究。在当前阶段,建议对患有细菌性脑膜炎的婴儿、2个月或2个月以上的小儿按个体情况给予地塞米松的治疗方案。二、在已发表的临床研究中所使用的方案是在抗生素治疗的头4天中,分4次静脉给予地塞米松
The American Academy of Pediatrics Infectious Diseases Commission recently released a new proposal for the use of dexamethasone in children with bacterial meningitis. Now excerpted from the following: First, dexamethasone is likely to reduce the possibility of Haemophilus influenzae meningitis may lead to deafness, although other than placebo-controlled studies are needed before absolute recommendations can be made. At this stage, it is advisable to treat children with bacterial meningitis with dexamethasone treatment on a case-by-case basis in children 2 months or more. Second, in the published clinical studies used in the program is in the first four days of antibiotic treatment, divided into 4 intravenous dexamethasone