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目的 :分析了“根治性”切除的 9例儿童小脑髓母细胞瘤长期临床观察 ,并研究其预后。方法 :对自 1990年 1月～ 2 0 0 2年 12月收治的 9例儿童小脑髓母细胞瘤患者全部行“根治性”切除术 ,病理证实。无瘤技术操作 ,“根治性”切除术的切除范围为肉眼肿瘤边缘外 1 5cm ,术后低剂量放射治疗后颅窝、脊髓 ,剂量相同。结果 :“根治性”切除术 9例儿童小脑髓母细胞瘤患者均存活至今 ,5年生存率为 10 0 %。结论 :对儿童小脑髓母细胞瘤外科手术应行无瘤技术操作 ,显微镜下切除肿瘤边缘外 1 5cm ,术后低剂量常规放射治疗。
OBJECTIVE: To analyze the long-term clinical observation of 9 cases of pediatric medulloblastoma removed by “radical” resection and to study their prognosis. Methods: Nine cases of pediatric patients with cerebellar medulloblastoma who were treated from January 1990 to December 2002 were all treated with “radical” resection and confirmed by pathology. Tumor-free operation, “radical” resection of the resection of the margins of the macroscopic tumor outside the 15cm, postoperative low-dose radiotherapy after the skull, spinal cord, the same dose. Results: The patients who underwent radical resection in all 9 cases of pediatric medulloblastoma survived so far, and the 5-year survival rate was 100%. CONCLUSION: Surgery of pediatric medulloblastoma should be performed without tumor technique. The tumor should be removed with a microscope under the edge of 15 cm. The low-dose conventional radiotherapy should be performed after the operation.