干燥综合征合并恶性肿瘤特别是恶性淋巴瘤临床常见,但合并急性髓细胞白血病罕见,现报告一例.患者女性,53岁,口、眼干燥2年未治疗,低烧乏力1个月住院.体查:体温37.4℃,贫血貌,口腔无出血点,肝脾及淋巴结不肿大,神经系统无异常.辅检:血红蛋白9.4g/dl,白细胞900/ml,其中原粒占32%.骨髓增生减低,原粒占50.8%,可见奥尔氏小体,过氧化酶及特异性酯酶阳性.γ球蛋白占28.3%,血沉107mm/小时.免疫学检查抗核抗体1 Sjogren’s syndrome with malignant lymphoma, especially malignant lymphoma clinical common, but the merger of acute myeloid leukemia is rare, a case is now reported .Female female, 53 years old, mouth, dry eye 2 years untreated, low fever, 1 month hospitalization. : Body temperature of 37.4 ℃, anemia appearance, no oral bleeding, no enlargement of liver and spleen and lymph nodes, no abnormalities in the nervous system.Auxiliary examination: hemoglobin 9.4g / dl, white blood cells 900 / ml, of which 32% , Accounting for 50.8% of the original particles, showing that Aurbus bodies, peroxidase and esterase-specific positive.Gamma globulin accounted for 28.3%, erythrocyte sedimentation rate 107mm / hour.Immunological examination of anti-nuclear antibody 1