在晚期肾功能衰竭患者中联用噻嗪类和袢利尿剂可提高疗效从理论上讲，噻嗪类阻断钠的重吸收应该能抵消袢利尿剂使用后重吸收钠的代偿性增多，从而提高钠利尿效果。为此，Ｆｌｉｓｅｒ等进行了一项随机交叉对照试验。１０例晚期肾功能衰竭患者在２周内进食含标准量钾和钠的... In patients with advanced renal failure with thiazide and 袢 diuretics can improve the efficacy Theoretically, thiazide blockade of sodium reabsorption should be able to offset 袢 diuretic reuptake after use of sodium compensatory increase, Thus increasing sodium diuretic effect. To this end, Fliser et al conducted a randomized controlled cross-over trial. Ten cases of patients with advanced renal failure within two weeks of eating with a standard amount of potassium and sodium ...